18 
Dr. Holn^es suggested that the RAC might follow either of two options; (1) 
recoimend Appendix B as proposed by the working group, or (2) retain ^^pendix 
B as it appears in the current Guidelines. He said he would suggest, as 
an amendment, that RAC retain Appendix B as it currently appears in the 
Guidelines. Dr. Bems disagreed; he said few substantive chcinges had been 
made in proposed Appendix B, and he would not accept Dr. Holmes' amendment. 
Er. Holmes withdrew his amendment. 
Mr. 'Ihomton called the question on Dr. Ahned's motion to recommend the 
proposed revised Guidelines, as amended. By a vote of eighteen in favor, 
none opposed, and no abstentions, the motion was accepted. 
Dr. Nightingale moved that, as suggested by the Working Group on Revision 
of the Guidelines, a RAC Working Group be appointed to periodically review 
the Guidelines. By a vote of eighteen in favor, none opposed, and no 
abstentions, the motion was accepted. 
Dr. Gottesnan said that one issue discussed by the Working Group on Revision 
of the Guidelines was IBC fmctioning under the revised Guidelines. She 
suggested that a letter might be sent to the IBCs covering the following 
issues: are the EBCs experiencing problems with the revised Guidelines, 
do the IBCs disagree with RAC in terms of contairment, are the Guidelines 
too stringent or too rel^u(ed, does the IBC spend inappropriate amotxits of 
time on any problem, how frequently do the conmittees meet, and does the 
coimittee fill other fijictions for the university, e.g., is the ooimittee a 
generad. biosafety committee? If the committee is not a general biosafety 
cormittee, why not? 
Dr. Gottesman said the effort would obviously be volmtary and the responses, 
therefore, would probably be somev^t biased; but the survey will at the 
miniman raise issues for discussion. 
VI. FVRJRE MEETING DATES 
Dr. Gartland said the next meeting was scheduled for October 25, 1982. He 
assumed it would be a one day meeting. 
VII. PRESE27TATICN OF CERTIFICATES OF SERVICE AND ADJOURNMEyT 
Mr. Ihomton said that the Joie 28, 1982, meeting would be the last 
meeting for six RAC members as their terms of service would expire on June 
30. The retiring members are Drs. Ahmed, Goldstein, Baltimore, Pinon, and 
Ms. King. Mr. Thomton said this meeting also was the last session of his 
term. He expressed his deep sense of friendship with mny members of the 
Recombinant DNA Advisory Committee. He said he had learned much frcm the 
members of the cammittee. He expressed his thanks to the NIH staff for the 
inv 2 duable si^iport they had given. He adso thanked Dr. Jim McCullough of 
the Congressional Research Service for his assistance over many jears. 
[477] 
I 
