5 
DK^ technolc3gy; now the report addresses medical surveillance in the biotech- 
nology industry. He said the heart of the report and the specific reconmenda- 
tions are essentiedly mchangedr although some alterations have been made to 
reflect specific conments and criticisms. Dr. Landrigan cedled the committee's 
attention to the revised document (Attachment I). 
Dr. Mason noted that the CDC/NIQ6H report classified antibiotics as reagent 
hazards; he asked how antibiotics would be used as reagents. Dr. Landrigan 
said antibiotics are used to control the gro%i^h of the organisms in the 
fermentation vessels. He said antibiotics sucii as ampicillin can cause 
gastrointestinal distress. 
Dr. Bems asked Cr. landrigan to explain epidemiologic^LI studies. Dr. Landrigan 
replied that epidemiological studies of industrial workers usually are a tri- 
partite effort by gwernnent, the industry and unions. In this instance, the 
industry bears initial primary responsibility. That responsibility would entail 
naintaining basic records, such as personnel records 2 uid records of specific 
exposures. 
Dr. Bems, noting that Ek. Miller had criticized the first draift of the CDC/NIOSH 
report, asked Ct. Miller if he had any conronts on this version. Cr. Miller 
said he found this version more acceptable than the first draft, but expressed 
a fundamented disagreement with the report's conclusions. He felt that the 
indiscriminate application of medical surveillance to the biotechnology indus- 
try is mlitely to be cost effective, and will be debilitating to industry. 
Dc, Bems questioned v^ether a pre-employment physical is standard practice in 
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