. 10 - 
PURP0S£S OF MEDICAL SURVEILLANCE 
Uncertainty provides the strongest argunent for aalntalnlng aedlcal 
surveillance over workers engaged In Industrial applications of 
biotechnology.^^ As Is the case for any newly developed technology, there 
is a lack of Information concerning the nature, or severity of any acute or 
chronic health hazards which night be associated with the Industrial 
applications of biotechnology. Given that lack of knowledge, the CDC/NIOSH 
Working Group Is of the opinion that nedical surveillance of biotechnology 
workers constitutes prudent nedical practice. Such surveillance should be 
aimed at the early detection of sentinel disease events. 
NATURE OF MEDICAL SURVEILLANCE 
In Its essence, nedical surveillance of biotechnology workers consists of 
periodic evaluation; regular analysis of data; and regular communication of 
results to workers, nanagement, and other Interested parties. 
The components of a nedical surveillance program for recombinant DMA workers 
which were considered by the Working Group are as follows: 
a. preemployment examination and collection of baseline serum samples for 
Storage; 
b. periodic follow-up examination; 
c. follow-up evaluation of all Illnesses which cause absence from work of 
K>re than 48 hours' duration; 
d. epidemiological and other longer term follow-up studies. 
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