268 
pedic guidelines by a very simple statement. This might take the following 
form: *‘The conditions of containment appropriate for any recombinant DNA 
experiment are those which are dictated by the most virulent or dangerous 
organism entering into that experiment.*’ Is anything more really required? 
I hope that none of you will construe any of my critical remarks as being 
personally directed. They are not. I have thoroughly enjoyed and been stim- 
ulated by my contacts with the many members of the Committee. I hope that 
I have established enduring friendships with many of you, and I shall certainly 
follow your further deliberations with great interest and concern. I should like 
particularly to express my appreciation to the several members of the NIH staff 
who have worked so hard and so loyally to keep this project afloat: Dr. Leon 
Jacobs who, from the beginning, hi^ served as Co-Chairman of this Committee, 
Dr. Bernard Talbot, who has worked enormously hard and valiantly. Dr. 
William Gartland, Director of the Office of Recombinant DNA Activities, his 
small but energetic staff — Dr. Kamely and Dr. Goldberg. Then, there is 
Ms. Betty Butler, who not only made certain that all the paper flowed in the 
right directions but also nursed us throuf^ our several tortured meetings. To 
work with all of these people has been a very rewarding experience. 
I wish you well in your future meetings. 
DeWitt Stetten, Jr. 
Deputy Director for Science 
National Institutes of Health 
Bethesda, MD 20014 (U.S.A.) 
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