CALIFORNIA INSTITUTE OF 
TECHNOLOGY 
PASADENA. CALIFORNIA 0112B 
DIVISION OF SIOLOOV tSS-SS 
AprU 15, 1981 
Dr. William Gartland 
Office of Recombinant DNA 
National Institute of General Medical Sciences 
Building 31, 4A52 
Bethes^, MD 20205 
Dear Dr. Gartland: 
I am writing to express my interest in emd approval of the proposal of Drs. 
Baltimore and Campbell (Federal Register ^ ^54, pp. 17994-7 of 3/20/81) for 
further changes In NIH guidelines for recombinant DNA research. The reduction in 
recommended containment levels simply represents good leiboratory practice in view 
of the experience that has been gained in the last five years. In addition, it seems 
particularly appropriate at this time of reduced financial support to eliminate 
regulatory provisions requiring a certain investment of time and money, and which 
have in any case applied only to research supported by NIH. If approved, this proposal 
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