UNIVERSITY OF CALIFORNIA, SAN FRANCISCO 
BERKELEY • DAVIS • IRVINE * LOS ANGELES • RIVERSIDE • SAN DIEGO • SAN FRANCISCO 
SANTA BARBARA • SANTA CRUZ 
SAN FKANCISOO, CALIFORNIA 94143 
(41 S) 666-4334 
22 April 1981 
SCHOOL OF MEDICINE 
DEPARTMENT OF BIOCHEMISTRY AND BIOPHYSICS 
Dr. Willieun Gartland 
Office of Recombinant DNA 
National Institute of General Medical Sciences 
Building 31 , 4A52 
Bethesda , Maryland 20205 
Dear Bill: 
I wish to comment on the proposals by David Baltimore and Allan Ccunpbell 
as outlined in the Federal Register of March 20, 1981 on pages 17994-7 
(Vol 46, No. 54). In view of their general knowledge and experience, I 
believe these proposals are eminently reasonable. Of crucial importance 
is that the guidelines would now set standards and provide guidance rather 
than regulate the performance of experiments. This change would certainly 
aid research in this area without, in my view, compromising attention to 
possible health hazards. 
Professor and Chairman 
kh 
15901 
