WRIGHT 
School of Medicine 
STATE 
Office of the Dean 
P O Box 927 
Dayton. Ohio 45401 
5ia/873-2933 
Wnght Slate University 
Dayton. Oh« 45435 
January 11, 1982 
Wllllaa J. Carcland, Jr., Ph.D. 
Director, Office of Recoablnant 
DNA Activities 
National Institutes of Health 
Building 31, Room 4A52 
Bethesda, HD 20205 
Dear Dr. Cartland: 
Thank you for the opportunity to review and to cooBKnt 
on the two proposals for a najor revision of the National 
Inatitutes of Health Guidelines for Research Involving Re- 
coab inant DNA Molecules. My colleagues and 1 find no major 
problems with either of the proposed revisions. We prefer 
the alternative appearing as item 7 in the Federal Register 
notice of December 7, 1981. 
Cordially, 
William D. Sawyer, M.D. 
Dean, School of Medicine 
Professor, Departments of Microbiology/ 
lamunology and Medicine 
WDSishw 
1651) 
