DEPARTMENT OF HEALTH AND HOSPITALS 
DAVID L. ROSENBLOOM 
Comminioner 
818 HARRISON AVENUE 
BOSTON, MASSACHUSETTS 02118 
January 12, 1982 
Director 
Office of Recombinant DNA Activities 
Building 31, Room 4A-52 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Sir/Madam: 
On behalf of the Boston Biohazards Committee, Department 
of Health and Hospitals, City of Boston, we wish to indicate our 
strong disagreement to the three current proposals for revision 
of existing guidelines for RDNA research (Baltimore-Campbell, 
RAC, and Gottesman) which appeared in the Federal Register of 
December 4, and 7, 1981. 
We support the continued measured and reasonable improvement 
in the current guidelines, but we believe that the current pro- 
posals in their present form are not consistent with this aim. 
Commissioner 
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