UNITED STATES DEPARTMENT OF AGRICULTURE 
SCIENCE AND EDUCATION ADMINISTRATION 
AGRICULTURAL RESEARCH 
NATIONAL PROGRAM STAFF 
BILTSVILLS, MARYLAND 30 70S 
Janusry 21, 1962 
SUBJTCT: Proposed Revisicns of NIH Guidelines for Research 
InvolTlng Recoabinant DMA Molecules 
TO: Vllliaa J. Gartland, Director 
Office of RecoMbinant DNA Activities 
National Institutes of Health 
Rooa AA52, Building 31 
Bethesda, Maryland 20205 
The tiR> proposals for a aajor revision of the NIH Guidelines for Research 
Involving Reooabinant DNA Molecules, published in the Federal Register . 
Deceaber A, 1981, and Deceaber 7, 1981, have been reviewed. Based on 
current scientific evidence, I recoaaend acceptance of the revision 
proposed by the Recoabinant DNA Advisory Coamittee. 
THOMAS J. MWT 
Deputy Administrator 
National Prograa Staff 
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