UNIVERSITY OF CALIFORNIA. RIVERSIDE 
BERKELEY • DAVIS • IRVINE • LOS ANGELES • RIVERSIDE • SAN DIEGO • SAN FRANCISCO 
SANTA BARBARA • SANTA CRDZ 
TELEPHONE: (714) 787-5535 
RESEARCH OFFICE 
RIVERSIDE, CALIFORNIA 92621 
January 27, 1982 
Dr. William J. Gartland, Jr. 
Di rector 
Office of Recombinant DMA Activities 
Building 31, Room 4A52 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Dr. Gartland: 
The Institutional Biohazards Coiranittee at the University of California, 
Riverside, unanimously recommends adoption of the proposed Revised 
Guidelines for Recombinant DNA Research which appeared in the 
December 4, 1981, Federal Register (46 FR 59368). It is our Committee's 
belief that relaxation of the federal guidelines is based on careful 
study by RAC and ORDA and that public safety is not jeopardized. 
Even if the December 4 guidelines are adopted, this campus will: 
a) Continue to employ the existing guidelines as a 
voluntary code of standard practice; 
b) retain the Institutional Biosafety Committee to 
serve as an advisory committee to certify proposed 
containment levels; and 
c) take advantage of the simplified containment levels. 
Thank you for the opportunity to comment on this important issue. 
Lei and M. Shannon, Chairman 
Institutional Biohazards Committee 
Dean, Graduate Division and 
Research Development 
LMS:svs 
cc: B. Cole 
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