UNIVERSITY OF CAUFORNIA, IRVINE 
BERKELEY • DAVIS • IRVINE • LOS ANOELES • RIVERSIDE • SAN DIE(,0 • SAN ERAM.ISU) 
SANIA HARBARA • SANTA CRUZ 
OFFICE OF THE CHANCELLOR 
IRVINE. CALIFORNIA 92717 
January 28, 1982 
Director 
Office of Recombinant DNA Activities 
National Institutes of Health 
Building 31, Room 4A52 
Bethesda, MD 20205 
Dear Director, 
In response to the proposals published in the December 4 and December 
7, 1981 Issues of the Federal Register , the University of California 
Irvine supports RAC’s December 4, 1981 proposal, calling for the voluntary 
compliance of institutions with NIH guidelines with respect to research 
involving recombinant DNA molecules. If this proposal were adopted, 
however, this cauqius would retain an active Institutional Biosafety 
Committee which would continue to monitor such research on the campus 
in accordance with all applicable regulations and good scientific 
practices. 
It would be expected that at the time that such a proposal became 
effective, the UC Irvine lostitutional Biosafety Committee would design 
policies and procedures for the campus for local institutional monitoring 
and control. 
Daniel G. Aldrich 
Chancellor 
[7061 
