2 
documents into a form completely consistent with my proposal nor will my wording 
be accurate in all instances. Also, I have not considered what should be done 
with part VI although it probably should be eliminated for the reasons set forth 
in Baltimore-Campbell. Another issue that is not adequately addressed in my 
version is the expansion of the RACs advisory role into other areas of biological 
research. 
The version I am submitting will, I believe, foster substantial "voluntary" 
attention to the central issue, namely, prudent approaches to new recombinant DNA 
experiments. It offers guidance to investigators in planning their experiments 
and urges on both investigators and institutions the need for consultation and 
review of novel studies. It emphasizes the fact that certain experiments remain 
questionable in many minds and should only proceed after extensive discussion 
with well-informed and responsible individuals under the aegis of the National 
Institutes of Health. I hope that the RAC will consider this proposal at its 
coming meeting. 
cc: 
Bernard Talbot 
Susan Gottesman 
Ray Thornton 
Paul Berg 
Sincerely yours. 
Maxine Singer, Ph.D. 
Chief, Laboratory of Biochemistry 
National Cancer Institute 
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