HARVARD UNIVERSITY 
The Biological Laboratories 
16 DrviNmr Avenuc 
Cammuocc. MAstACHUirm 021S8 
Jamiary 28, 1982 
Willlaa J. G«rtland, Jr., Director 
Office of Reconblnant DNA Actlvltlee 
National Inatltutea of Health 
Building 31 Room 4A52 
Bathesda, HD 20205 
Dear Dr. Gartland: 
I want to reglater my opposition to tha Baltlmora/Campbell 
proposal descrlbad In the Federal Register of December 4, 1981, 
which would convert the NIH Guidelines to voluntary and would 
also weaken them In several respects. 
I feel that this moment, when many new, small companies are 
still being formed and their standards of activity and mutual 
relationships are not at all clear. Is not the correct time to 
weaken the Guidelines and lift thalr mandatory character. 
Furthermore, I am vary concerned over the serious conflict 
of Interest that exists In having Dr. Baltimore being heavily 
Involved In deregulation proceedings. Dr. Baltimore Is treated 
as though hs were speaking as a disinterested, academic scientist, 
irhen he. In fact, has a large financial Interest In a commercial 
firm (Collaboratlfve Genetics) that stands to profit from the 
deregulation he proposes. 
To keep a modicum of confidence In the ethical conduct of 
the scientific community. It seems Imperative that commercial 
connections be publlcally acknowledged and that all conflicts 
of Interest of this sort ba avoided. 
For these and other reasons, I think that tha Got teaman 
proposal Is far preferable at this time. 
^_,„_Slncerely yours, 
Ruth Hubbard 
Professor of Biology 
[71 7J 
