osu 
Th« OMo State UnivaraHy 
Graduate School 
University Mali 
230 North Oval Mail 
Columbus, Ohio 43210 
Phone 614 422-6031 
January 29, 1982 
Director 
Office of Recombinant DNA Activities 
Building 31, Room 4A52 
National Institutes of Health 
Bethesda, Maryland 20205 
Dear Sir: 
The Institutional Biosafety Committee of The Ohio State University 
has studied the "RAC Proposal" and the "Gottesman Proposal" for 
modification of the NIH Guidelines for Research Involving Recombinant 
DNA Molecules. By a vote of 9:1 of the members in attendance, the 
IBC voted approval of the RAC Proposal. Upon the recommendation 
of the IBC, The Ohio State University endorses the RAC Proposal and 
urges its final approval by the RAC and by the Director of the NIH. 
If this modification of the NIH Guidelines goes into effect. The 
Ohio State University will disband its Institutional Biosafety 
Committee and handle safety considerations for recoirtinant DNA 
research by the same procedures used in other area of research. 
T . 
Associate Dean for Research 
TRD/jl 
1740 ] 
