Irwnn O.J. Bros*. Pti.O. 
0«r*ctof o< Btoauiittics 
Ro«w«ll Park Memorial Inatilute 
666 Elm Street 
Butlalo. N Y 14263 
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February 1, 1982 
William J. Gartland, Jr. 
Director 
Office of Recombinant DMA Activities 
National Institute of Health 
Building 31 Room 4A52 
Bethesda, Maryland 20205 
Dear Sir: 
The Baltimore/Campbell proposal described in the Federal 
Register would eliminate any meaningful controls of Recombin£uit DNA 
Technology and would create a major hazard to the public health and 
safety. 
I share the concerns outlined in the well reasoned letter from 
Donna Smith and Terri Goldberg and %rould support the Gottesman proposal. 
However, with the "gold rush" now on in biotechnology, I am afraid that 
the pressure for deregulation is overwhelming. A disgraceful chapter in 
American science that future historians will write is the complete 
failure of courage, will, and integrity of the U.S. scientists who 
capitulated to this pressure. 
My purpose here is to note in the official record the personal 
liability of all persons, possibly including yourself, who implement the 
Baltimore/Campbell proposal. Sooner or later someone in the "gold rush" 
will taJce one shortcut too many and there will be human deaths ^uld 
disabilities as a consequence of the deregulation of Recombinant DNA 
Technology. 
Before the fact, let me note that due warning has been regis- 
tered in this letter and that NIH has disregeurded this warning. Therefore, 
all persons who inclement the Baltimore/Campbell proposal will be 
personally liable for any civil and criminal penalties that may result 
from the public health hazards created by this proposal. 
IDJB/maJc 
Enc. 
[ 765 ] 
