TABLE OF CONTENTS 
1.0 Objectives 
2.0 Rational for Current Protocol: Scientific and Therapeutic 
Justification (Includes Brief Study Outline) 
3 . 0 Background 
4.0 Patient Eligibility 
5.0 Treatment Plan 
6 . 0 Concurrent Treatment and Supportive Care 
7.0 Autologous Bone Marrow and Peripheral Blood Stem Cell 
Harvesting, Cell Separation and Cryopreservation of Cells 
8 . 0 Pre-study Evaluation 
9.0 On-Study Evaluation 
10.0 Toxicity Monitoring 
11.0 Dose Modifications 
12.0 Hazards and Discomforts 
13 . 0 Response Criteria 
14.0 Criteria for Removal from Study 
15.0 Biostatistical Analysis 
16.0 References 
17.0 Appendices 
A. ECOG Performance Status 
B- -Dartmouth Bone Marrow Transplant Criteria 
C. . Radiotherapy Guidelines and Information 
D. Drug Information 
E_. Interferon Toxicity Criteria 
F. GM-CSF Toxicity Criteria 
G. Treatment Flow Diagram 
H. On-Study Evaluation Flow Diagrams 
. 18 . 0. Inf ormed. Consent Form for Protocol 
Recombinant DNA Research, Volume 16 
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