MEDICAL RECORD 
CONTINUATION SHEET for either: 
NIH 2514-1, Consent to Participate In A Clinical Research Study 
NIH 2514-2, Minor Patient's Assent to Participate In A Clinical Research Study 
S^'iDY NUMBER: . CONTINUATION: page J__of pages. 
urine will turn red for several hours after the infusion due 
to a red dye in the freezing liquid. You may develop a fever 
the evening after the infusion. Some patients can develop 
allergic reactions to the reinfusion of cells, with symptoms 
including shortness of breath, hives, fever, and kidney 
damage . 
7) Post-Transplant Care: After the bone marrow and peripheral 
blood stem cell transplantation, you will be very sick for 
three or more weeks while waiting for the infused cells to 
migrate to the bone marrow cavity and to begin to produce 
blood cells again. You will be susceptible to infections due 
to a very low white blood cell count. Your nurses and doctors 
will take many precautions to try and protect you from 
developing an infection, and you will be given several 
medications to try and prevent certain types of infections 
that are known to be common in bone marrow transplant 
patients. You will be in a private room, and adults with any 
symptoms of infection or any children under 12 will be 
prevented from visiting you. If you develop a fever, you will 
have many blood and X-ray tests done to look for an infection, 
and you will be placed on one or more very strong antibiotics. 
You will again be given the drug G-CSF beginning one day after 
the transplant to try and speed up the recovery of your white 
blood cells, but this treatment can not prevent the period of 
low white blood cell counts altogether. (See #2) above for 
more information on G-CSF). - 
Despite all of these precautions and treatments, it is 
possible that you will develop a very serious infection that 
we can not control with antibiotics. This is the most 
significant risk from this transplantation procedure, and 
there is a small but real risk that you could die from this 
complication. You will also be at an increased risk of 
bleeding until your bone marrow recovers. You will receive 
many platelet and red blood cell transfusions for at least 3 
weeks after the transplant. 
Other side effects of the very high-dose chemotherapy and 
radiation include a higher risk of developing other 
malignancies later in your life, and a serious type of liver 
damage called veno-occlusive disease that sometimes occurs in 
patients after bone marrow transplant. You will also probably 
not be able to eat or drink for several weeks after the 
transplant due to mouth sores, and you will require 
PATIENT IDENTIFICATION 
CONTINUATION SHEET for either: 
i 
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NIH-2514-1 (10-84) 
Recombinant DNA Research, Volume 16 
