MEDICAL RECORD 
CONTINUATION SHEET for either: 
NIH 2514-1, Consent to Participate In A Clinical Research Study 
NIH 2514-2, Minor Patient's Assent to Participate In A Clinical Research Study 
° T UDY NUMBER: 
CONTINUATION: page JL_ of pages. 
intravenous feeding until you are able to eat normally. 
It is also possible that the bone marrow and peripheral blood 
stem cells will not grow at all once they are given back to 
you. This complication is rare, less that 5% in other groups 
of patients with multiple myeloma that have received this type 
of treatment. However, if it does occur it usually results in 
death. You will be getting back both bone marrow and 
peripheral blood stem cells, which reduces but does not 
completely eliminate this risk. 
8) After the transplant, it will be necessary to draw blood 
once a day or even more frequently until marrow recovery. 
Amounts will vary, but most often will be 2-6 tablespoons at 
a time. Samples of blood (up to 4 tablespoons at a time) will 
also be drawn weekly then monthly for research purposes to try 
and learn more about your disease and the transplant 
procedure. With your consent, you may also be asked to 
undergo pheresis after marrow recovery to obtain enough cells 
for research studies. 
You will have bone marrow samples taken from your hip bone at 
the bedside every week until your marrow recovers, and then 
every three months to monitor the state of your disease and 
your marrow recovery. • 
You may also receive periodic chest X— rays and other radiology 
tests to monitor you for possible infections. 
Once your bone marrow has engrafted (recovered in your body), 
and you have adequate blood values, and you are free from 
infection, you will be discharged from the hospital. We 
expect this will take 4-6 weeks from the day of 
transplantation. You will be followed closely in the out- 
patient clinic up until at least 60 days post- transplant . We 
will continue to draw blood twice weekly to check your blood 
counts and some body function tests (such as liver function) . 
After day +60 you will begin monthly evaluations at NIH to be 
continued for the first year post-transplant. These visits 
will include blood tests and a general assessment of your 
condition. A bone marrow biopsy and aspirate (approximately 
30 ml or about 2 Tablespoons of marrow withdrawn) will be done 
every three months. Larger samples of blood (50 ml. or 3-4 
Tablespoons) will also be collected every three months. This 
will allow us to closely monitor your health status and 
PATIENT IDENTIFICATION 
CONTINUATION SHEET for either: 
NIH-2S14-1 (10-84) 
Recombinant DNA Research, Volume 16 
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