All fatal events (Grade 5). 
All first occurrences of any previously unknown toxicity 
(regardless of grade). 
14.0 Response Criteria : 
Complete Response : No evidence of disease on restaging one month 
after bone marrow transplant persisting for 4 weeks. 
Complete Response - Unconfirmed : No evidence of active disease on 
restaging one month after bone marrow transplant, but the presence 
of residual masses clinically consistent with benign residual 
fibrosis. 
Partial Response : A 50% or greater reduction in the size of 
measurable lesions as defined by the sum of the products of the 
longest perpendicular diameters of all measurable indicator lesions 
for at least one month. 
Minor Response : A 25% to 49% reduction in the size of the 
measurable lesions as defined by the sum of the products of the 
longest perpendicular diameters of all measurable indicator lesions 
for at least one month. 
Stable Disease : Tumor size not showing evidence of response or 
progression. 
Progressive Disease : An increase of 25% or more in the size of 
measurable lesions as defined by the sum of the products of the 
longest perpendicular diameters of all measurable indicator lesions 
compared to the smallest previous measurement, or the appearance 
of a new lesion. 
Recombinant DNA Research, Volume 16 
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