* * * TABLE OF CONTENTS * * * 
I. Call to Order 5 
II. Minutes of June 1-2, 1992, Meeting 5 
III. Proposed Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled: A Study of the Safety and Survival of the 
Adoptive Transfer of Genetically Marked Syngeneic Lymphocytes in HIV Infected 
Identical Twins /Drs. Walker and Blaese 5 
IV. Proposed Addition to Appendix D of the NIH Guidelines Regarding a 
Semliki Forest Virus Helper Expression System/Dr. Temple 14 
V. Presentation: Financial Obligation of Research Institutions to 
Patients/Dr. McCarthy 19 
VI. Presentation: Radiation and Mutation Rates in Human 
Populations/Dr. Neel 23 
VII. Proposed Additions to Appendix D of the NIH Guidelines Regarding Three 
Human Gene Transfer Protocols Entitled: (1) Phase I /II Study of the Use 
of Recombinant Human Interleukin 3 Stimulated Peripheral Blood Progenitor 
Cell Supplementation in Autologous Bone Marrow Transplantation (ABMT) in 
Patients with Breast Carcinoma or Hodgkin's Disease, (2) Evaluation of the Use 
of Recombinant Human Granulocyte Colony Stimulating Factor (G-CSF) 
Stimulated Peripheral Blood Progenitor Cell Supplementation in Autologous 
Bone Marrow Transplantation in Patients with Lymphoid Malignancies, and (3) 
A Trial of G-CSF Stimulated Peripheral Blood Stem Cells for Engraftment in 
Identical Twins/ Dr. Schuening 27 
VIII. Addition to Appendix D of the NIH Guidelines Regarding the Introduction 
of a Gene Coding for Tetracycline Resistance into Porphyromonas 
Gingivalis/ Dr. Progulske-Fox 41 
IX. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Use of Retroviral Markers to Evaluate the 
Efficacy of Purging and to Discriminate Between Relapse Which Arises 
From Systemic Disease Remaining After Preparative Therapy Versus Relapse 
Due to Residual Neoplastic Cells in Autologous Marrow Following Purging 
in Patients with Chronic Lymphocytic Leukemia (CLL)/ Dr. Deisseroth 42 
Recombinant DNA Research, Volume 16 
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