5.5 Monitoring 
5.5.1 Safety and Toxicity 
Prior to entry both donor and recipient will undergo complete medical 
history, physical examination, laboratory investigations, 
electrocardiogram, and chest x-ray as outlined in Table 3 and Table 4. 
Complete medical history: 
-duration of diagnosis of HIV infection (for recipients), disease 
manifestations, and complications 
-history of all known allergies 
-history of opportunistic infections and malignancies 
-history of sexually transmitted diseases including gonorrhea, syphilis, 
hepatitis, mononucleosis, CMV infection, herpes, and parasitic diseases 
-current medications, including over-the-counter preparations 
-history of substance abuse and recreational drug use 
-history of depression, anxiety, mental illness, emotional problems, use of 
psychiatric medications, and previous psychotherapy 
-knowledge and practice of "safe sex" 
-current contraceptive practices 
-surgical procedures and results 
-rate of KS progression, including date of KS diagnosis, for patients with 
KS 
Complete physical examination: 
-performance status (Table 1) 
-weight 
-height 
-vital signs 
-pulmonary examination 
-cardiac examination 
-abdominal examination 
-neurologic examination 
-oropharyngeal examination 
-stool guaiac 
Laboratory and other investigations (to be done at screening, entry, and 
follow-up visits according to the schedules in Table 3 [recipient] and 
Table 4 [donor]): 
-CBC and differential 
-platelet count 
-reticulocyte count 
-PT and PTT 
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