Figure 1.9. 5 -A. Schematic of the anatomy of the bronchial tree typical for 
cystic fibrosis in midcourse. The cut-away view shows details of the epi- 
thelium and submucosal glands. There are changes to the epithelium with a 
loss in ciliated cells and an increased number of secretory, basal and 
undifferentiated columnar cells. The submucosal glands are hypertrophied in 
some areas and thinned in others. There is thick, purulent mucus in the 
glands and in the airways . 
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Recombinant DNA Research, Volume 16 
