5.6.2-A 
BASELINE PERIOD 1 
Initial evaluation 
minimum of 1 week 
before day 1 , 
Sample epithelium 
Left and right nostril 
Left and right bronchi 
Safety and efficacy parameters 2 
General assessment 
Dyspnea index 
General blood 
CBC, ESR 
Clotting 
Chemistry 
Other 
General immunity 
Culture 
HIV 
Urine 
Routine 
Culture 
24 hr 
Sterility evaluation 
EKG 
Roentgenographic 
Chest X-ray 
Chest CT 
Scintigraphic 
Lung function 
Spirometry 
He dilution, DLCO 
Body box 
ABG 
Sputum 
Volume 
Culture 
Bronchoalveolar lavage 
Nasal brush 
Bronchial brush 
Potential difference 
Vector-related 
Anti-Ad antibodies 
Adenovirus culture 
Adenovirus DNA 
Serum TNF 
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