he stated that "ultimately the discus- 
sion, kinds of facility and guidelines 
are simply irrelevant.” In his view, 
human security may be threatened by 
"the biologic revolution." He notes tht 
Just as the "nuclear reality” has led to 
the term "omnicide,” and environmen- 
tal pollution to "ecocide," biological 
research may lead to “genecide.” 
As noted in my Decision document 
(Federal Register,) July 28, 1978), 
NIH has been asked to provide a 
forum for dealing with social issues re- 
latig to "genetic engineering.” The 
concerns of this witness may be taken 
in the same context. My Decision 
notes that NIH has been addressing 
the policy questions involving the 
safety of this research, not the "poten- 
tential future application * • * to the 
altering of the genetic character of 
higher forms of life, including man 
* * *. In light of public concern, a 
study is warranted of the ethical, 
legal, and social implications of these 
techniques. The National Commission 
for Protection of Human Subjects of 
Biomedical and Behavioral Research 
considered, but was unable to initiate, 
a study * • Such a study might be 
considered by the Department’s newly 
created Ethical Advisory Board. It 
could also be a key priority for the Na- 
tional Commission for the Protection 
of Human Subjects, which was reauth- 
orized by the Congress before adjourn- 
ment of this session. 
Appendix II— Federal Interagency Adviso- 
ry Committee on Recombinant DNA Re- 
search, October 1978 
DEPARTMENT OF AGRICULTURE 
Dr. James Nielson, Deputy Assistant Secre- 
tary for Conservation. Research, and Edu- 
cation, U.S. Department of Agriculture, 
Washington. D.C. 20250. 
Charles F. Lewis, Ph. D. (Alt.), Staff Scien- 
tist, Plant and Entomological Sciences, 
National Program Staff, ARS, USDA, 
BARC-West, Beltsville, Maryland 20705. 
Dr. Clarence O. Grogan (Alt.), Principal 
Agronomist. Conservation, Research, and 
Education. U.S. Department of Agricul- 
ture, Washington, D.C. 20250. 
DEPARTMENT OF COMMERCE 
Jordan J. Baruch, Sc. D., Assistant Secre- 
tary for Science and Technology, U.S. De- 
partment of Commerce, Washington. D.C. 
20230. 
DEPARTMENT OF DEFENSE 
William R. Belsel, M.D., Scientific Adviser. 
U.S. Army Medical Research Institute of 
Infectious Diseases, Ft. Detrick, Frederick, 
Maryland 21701. 
DEPARTMENT OF HEALTH, EDUCATION, AND 
WELFARE 
Lowell T. Harmison. Ph. D.. Science Adviser. 
Officer of Health Policy, Research, and 
Statistics. OASH, Parklawn Building, 
Room 17A-55, Rockville, Maryland 20857. 
NOTICES 
CENTER FOR DISEASE CONTROL 
* 
John H. Richardson, D.V.M., Director, 
Office of Biosafety. Center for Disease 
Control, Atlanta. Georgia 30333. 
Anthony Robbins. M.D., Director, National 
Institute for Occupational Safety and 
Health, Parklawn Building, Room 8-05, 
Rockville, Maryland 20857. 
FOOD AND DRUG ADMINISTRATION 
Robert L. Elder, Sc. D., Deputy Associate 
Commissioner for Science, Food and Drug 
Administration, Parklawn Building, Room 
14-57, Rockville, Maryland 20857. 
Rosa M. Gryder, Ph. D. (Alt.), Staff Science 
Adviser. Office of Science, Food and Drug 
Administration, Parklawn Building, Room 
7-83, Rockville, Maryland 20857. 
John C. Petricclani, M.D., Deputy Director, 
Division of Pathology, Bureau of Biolo- 
gies, FDA, NIH Building 29, Room 514, 
Bethesda, Maryland 20014. 
DEPARTMENT OF ENERGY 
James L. Liverman, Ph. D., Deputy Assist- 
ant Secretary for Environment, Depart- 
ment of Energy, Washington. D.C. 20545. 
Charles E. Carter, M.D. (Alt.), Manager, 
Biomedical Programs, Office of Health 
and Environmental Research. Department 
of Energy, Washington, D.C. 20545. 
Walter H. Weyzen, M.D. (Alt.), Manager, 
Human Health Studies Programs, Office 
of Health and Environmental Research, 
Department of Energy, Washington, D.C. 
20545. 
DEPARTMENT OF INTERIOR 
Mariano Pimentel. M.D., Medical Director, 
Department of Interior, 18th and C 
Streets, NW„ Room 7045, Washington, 
D.C. 20240. 
DEPARTMENT OF JUSTICE 
Mr. Anthony Liotta, Deputy Assistant At- 
torney General, Land and Natural Re- 
sources Division, Department of Justice, 
Washington. D.C. 20530. 
DEPARTMENT OF LABOR 
Eula Bingham, Ph. D., Assistant Secretary 
for Occupational Safety and Health, De- 
partment of Labor, Washington, D.C. 
20210. 
DEPARTMENT OF STATE 
Mr. William J. Walsh III, Biomedical Re- 
search Liaison and Health Affairs Officer,, 
Bureau of Oceans and International Envi- 
ronmental and Scientific Affairs, Depart- 
ment of State, Washington, D.C. 20520. 
DEPARTMENT OF TRANSPORTATION 
Mr. Douglas A. Crockett, Department of 
Transportation. Trans Point Building. 
Room 6405, 2100 Second Street SW„ 
Washington, D.C. 20590. 
ENVIRONMENTAL PROTECTION AGENCY 
Thomas A. Murphy, Ph. D., Acting Deputy 
Assistant Administrator for Health and 
Ecological Effects, Environmental Protec- 
tion Agency, 401 M Street, SW.. Washing- 
ton, D.C. 20460. 
EXECUTIVE OFFICE OF THE PRESIDENT 
Gilbert S. Omenn, M.D., Ph. D.. Assistant 
Director for Human Resource#, Office of 
Science and Technology Policy, Old Ex- 
60103 
ecutlve Office Building, Room 360. Wash- 
ington, D.C. 20500. 
Mrs. Carroll L. Bastian, Senior Staff 
Member for Environmental Health and 
Toxic Substances. Council on Environ- 
mental Quality. 722 Jackson Place, NW., 
Washington, D.C. 20006. 
NATIONAL AERONAUTICS AND SPACE 
ADMINISTRATION 
David L. Winter, M.D.. Director for Life Sci- 
ences, National Aeronautics and Space Ad- 
ministration, 400 Maryland Avenue SW"., 
Room 5111. Washington. D.C. 20546. 
NATIONAL SCIENCE FOUNDATION 
Herman W. Lewis, Ph. D., Section Head of 
Cellular Biology, Division of Physiology, 
Cellular, and Molecular Biology, National 
Science Foundation, Washington. D.C. 
20550. 
Philip D. Harrlman, Ph. D., Program Direc- 
tor of Genetic Biology, National Science 
Foundation, Washington, D.C. 20550. 
NUCLEAR REGULATORY COMMISSION 
Mr. Frank Swanberg. Jr., Chief, Health, and 
Environmental Research Branch, Nuclear 
Regulatory Commission, Washington. 
D.C. 20555. 
U.S. ARMS CONTROL AND DISARMAMENT AGENCY 
Rbbert Mikulak. Ph. D., Physical Science 
Officer, Multilateral Affairs/ Advanced 
Technology, U.S. Arms Control and Disar- 
mament Agency, Washington, D.C. 20451. 
VETERANS’ ADMINISTRATION 
Jane S. Schultz, Ph. D., Chief, Program 
Review Division, Veterans' Administration 
Central Office, 810 Vermont Avenue, NW., 
Room 755, Washington, D.C. 20420. 
CHAIRMAN OF THE COMMITTEE 
Donald S. Fredrickson, M.D., Director, Na- 
tional Institutes of Health, Bethesda. 
Maryland 20014. 
EXECUTIVE SECRETARY OF THE COMMITTEE 
Joseph G. Perplch, M.D.. J.D., Associate Di- 
rector for Program Planning and Evalua- 
tion, National Institues of Health, Bethes- 
da, Maryland 20014. 
Appendix III 
EXCHANGE OF LETTERS BETWEEN SENATORS AND 
SECRETARY CALIFANO 
[ Letter to Senator Kennedy attached; 
similar letters were sent to the five other 
Senators J 
United States Senate, 
Washington, D.C., June 1, 1978 
Hon. Joseph A. Califano, Jr., 
Secretary of Health, Education and Welfare, 
Department of Health, Education and 
Welfare, Washington, D.C. 20201. 
Dear Mr. Secretary: Since 1976 four com- 
mittees of the House and Senate have held 
nine series of hearings to consider the issues 
relating to recombinant DNA research. 
These extended and thorough inquiries 
have shown that, with respect to the re- 
search they support and conduct, the Na- 
tional Institutes of Health have taken a 
properly cautious approach by prohibiting 
certain presumably hazardous experiments, 
requiring certification of the safety of' host- 
vector systems, prescribing physical and bio- 
logical containment measures for the con- 
FEDERAl REGISTER, VOL 43, NO. 247— FRIDAY, DECEMBER 22, 1978 
[ 26 ] 
