6 
below. See Section II-A-3 for procedures for other classes of NIH 
awards . 
II-A-1. Elements of an MUA . An MUA must contain the following 
sections: 
II-A-l-a. Description . There must be a description of each 
proposed project, and the name of the individual investigator responsible 
for the research if other than the Principal Investigator. 
Descriptions must include information on (i) the source(s) of DNA, 
(ii) the nature of inserted DNA sequences, and (iii) the hosts and 
vectors to be used. The descriptions rrust provide sufficient informa- 
tion about the experiments so that reference to other documents is not 
required. For each performance site, the organization name(s), the 
city, and the State must be stated. The description for each series of 
experiments can ordinarily be held to two pages. 
II-A-l-b. Assessment of Containment Levels . There must be an 
assessment of the physical and biological containment levels required by 
the NIH Guidelines for each series of experiments, with citation of the 
relevant sections of the Guidelines or announcements from ORDA. 
II-A-l-c. Information on Health Surveillance . Information must be 
provided on the Institution's determination of the necessity, in connec- 
tion with each project, for health surveillance of recombinant DMA 
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