21 
(i) the source (s) of DNA, (ii) the nature of inserted DNA sequences, and 
(iii) the host-vector system(s) being used. Ordinarily, no more than two 
pages of description for each series of experiments are necessary. 
III-C-1-g. An assessment of the level (s) of physical and 
biological containment required by the Guidelines for each series of 
experiments . 
Ul-C-l-h. a statement that an Institutional Biosafety Committee 
(IBC) has reviewed the project and found it to be in compliance with the 
NIH Guidelines. 
m-C-l-i. The signatures of the Principal Investigator, the 
chairperson of the IBC, and the institutional official. The Institution 
may designate the IBC chairperson as the responsible institutional 
official. 
UI-C-1-j. The date of signature by the institutional official. 
This date will be used for reference purposes. 
HI— D. Review of Non-NIH-Supported Projects . Institutions and 
Federal agencies will be notified in writing of ORDA's review of the 
information submitted for registration of recombinant DNA projects not 
supported by NIH. If review by ORDA finds that the protocols do not 
conform to standards set forth in the Guidelines, the Institution shall 
take appropriate action to bring the protocols into compliance. 
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