In sum, we would like to make the following recommendations: That the 
Secretary of HEW take control of recombinant DNA activities under Sec. 361 
of the Public Health Service Act or similar existing authorization; that 
his control extend to all recombinant DNA activities in this country, 
including those not supported by the NIH or other government agencies; and 
that he set up an Advisory Committee including representatives from other 
relevant agencies such as EPA, OSHA, CDC, etc., as well as disinterested 
individuals in various fields relevant to the public interest. Some 
appropriate fields for the members of such a committee have been listed in 
the Senate Joint Resolution No. 71, presented by Mr. Mondale in March, 1973, 
and in the recent bill HR7897. Nominations for committee membership should 
be solicited from the public and from interested organizations, and the 
appointments should reflect a wide spectrum of viewpoints. The Advisory 
Committee, with the help of technical subcommittees appointed by the 
committee as needed, should 1) review and revise the guidelines in the 
future; 2) review and approve or disapprove all proposed recombinant DNA 
projects that have been approved by local comnittees; 3) review and make 
recommendations to the Secretary concerning proposed exemptions from the 
guidelines, reductions in containment, or other waivers; 4) make a study 
of proposed industrial applications and proposed operations involving 
deliberate release of recombinant organisms into the environment, in order 
to determine whether there is sufficient hard scientific data on which 
to base a meaningful risk/benefit analysis in the public interest; and 5) 
the committee should see that such an analysis is carried out before 
authorization of such activities, or it should propose further risk 
assessment experimentation or the development of new safety measures qt the 
acquisition of additional basic information } when these are deemed necessary 
for adequate judgment of a proposed recombinant DNA activity. Public 
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