INTERAGENCY COMMITTEE ON RECOMBINANT DNA RESEARCH 
Summary Minutes of Meeting 
October 12, 1978 
National Institutes of Health 
Bethesda, Maryland 
The ninth meeting of the Interagency Committee took place on Thursday, 
October 12, from 2:30-4:30 at the National Institutes of Health. The 
meeting was chaired by Dr. Donald Fredrickson, Director of the NIH. 
The meeting was devoted to a review of (1) the NIH Proposed Revised 
Guidelines, (2) the role of the Interagency Committee (IAC) in the 
revised Guidelines, and (3) agency comments on the Guidelines and the 
role of the IAC. 
I. Review of the NIH Proposed Revised Guidelines (PRG) 
Dr. Fredrickson opened the meeting by presenting an outline of 
events leading to the proposed revision of the NIH Guidelines, 
including : 
• Phase I — the promulgation of the NIH Guidelines in June 1976. 
• Phase II — the creation of the Interagency Committee in the 
Fall, 1976; subsequent oversight and legislative review in 
Congress, but no law; and the administration of the NIH 
Guidelines . 
• Phase III — began with revised Guidelines proposed by the RAC in 
September 1977. 
Before examining proposed procedural revisions of interest to the 
Committee, Dr. Fredrickson briefly summarized major technical 
changes in the Guidelines. 
II. Proposed Role of the Interagency Committee (IAC) in the Proposed 
Revised Guidelines 
A number of measures to encourage Federal agency participation in 
decisions on recombinant DNA research were outlined by 
Dr. Fredrickson. 
[ 427 ] 
