3 
B. Additional Procedures to Assure Consideration of Agency Views 
1. Liaison membership would allow Federal agency participation in 
certain decisions, for example, RAC interpretation of 
Guidelines and recommending changes in containment levels for 
experiments not considered in the Guidelines. 
2. In addition to liaison membership on the RAC, Federal agency 
participation will be specifically sought after certain RAC 
actions during the public comment period, such as 
recommendations on waivers of prohibitions, new prohibitions, 
additions to the list of exemptions, certification of 
host-vector systems, and changes (including revisions and 
amendments) in the Guidelines. Plans call for all Interagency 
Committee members to receive advance Federal Register notices 
of these RAC actions for their comment. 
The possibility of a consensus meeting of the Interagency 
Committee on particular RAC actions, such as a recommendation 
to release a recombinant organism into the environment, is 
envisioned. 
3. A three step appeal mechanism for RAC actions will be provided 
to Federal agencies: 
(1) consultation with ORDA 
(2) direct conmunication with the Director, NIH 
(3) provision for any agency to request a meeting of the 
Interagency Committee to consider RAC action in light of 
the agency's concern. 
It was noted by Dr. Fredrickson that there are currently no 
regularly scheduled Interagency Committee meetings; however, 
there will probably be a need for periodic meetings in the 
future. 
C. Agency Resource 
ORDA will provide consultation to all Federal agencies regarding 
the Guidelines. 
D. Registration 
In institutions where NIH funds recombinant DNA research two 
registration options are proposed: 
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