UNITED STATES DEPARTMENT OF COMMERCE 
The Assistant Secretary for Science and Technology 
Washington. D.C. 2Q230 
(202) 377-3111 
04 MJ& 1978 
Dr. Donald S. Fredrickson 
Director 
National Institutes of Health 
Bethesda, Maryland 20014 
Dear Don: 
Thank you for sending me the three documents concerning 
the National Institutes of Health (NIH) Proposed Revised 
Guidelines to control recombinant DNA research funded 
by the NIH. 
As you know, I continue to be deeply interested in the 
recombinant DNA issue. If we have any observations to 
make during the period of public comment, beyond those 
already made at the meetings of the Interagency Committee, 
I will have Sid Galler pass them to Joe Perpich. 
[A-4] 
