ST. JUDE CHILDRENS RESEARCH HOSPITAL 
332 North Lauderdale, PO Box 318, 
Memphis, Tennessee 38101 
(901) 525-8381 
Danny Thomas, Founder 
24 August 1978 
Dr. Donald S. Fredrickson 
Director 
National Institutes of Health 
Building 1, Room 124 
9000 Rockville Pike 
Bethesda, MD 20014 
Dear Dr. Fredrickson: 
I am writing as a practicing molecular biologist to urge the 
adoption of the Proposed Revised Guidelines for recombinant DNA 
research funded by the National Institutes of Health, as published 
in the Federal Register of 28 July, 1978. 
According to past and recent experience, potential hazards of 
this research were imaginatively overestimated by some individuals. 
There now seems to be no justification for continuing to enforce 
restrictions that are scientifically unsupported and which are 
interfering with the performance of work for the benefit of society. 
Sincerely, 
David W. Kingsbury 
DWK/jh 
