THE UNIVERSITY OF NORTH CAROLINA 
AT 
CHAPEL HILL 
Division of Health Affairs 
The School of Medicine 
Department of Bacteriology and Immunology 
August 30, 1978 
The University of North Carolina at Chapel h 
804 Faculty Laboratory Office Building 23 1 H 
Chapel Hill, N.C. 27514 
Dr. Donald S. Fredrickson 
Director 
National Institutes of Health 
9000 Rockville Pike 
Bethesda, Maryland 20014 
Dear Dr. Fredrickson: 
In the absence of any documentable evidence or consensus within 
the scientific community that recombinant DNA research poses a 
hazard to society I find the entire concept of Research Guidelines 
repugnant. The new proposed Guidelines continue to restrict 
research and greatly reduce the output of recombinant DNA researchers. 
In as much as there is a small reduction in the outrage embodied in 
the proposed Guidelines they represent a tiny step in the right 
direction. We need many more such steps 
Sincerely, 
^curbhoit Hail EbUj^il 
Marshall Hall Edgell, Ph.D 
Professor 
[A-64] 
