HARVARD UNIVERSITY 
The Biological Laboratories 
16 Divinity Avenue 
Cambridge, Massachusetts 02138 
September 5, 1978 
Dr. Donald S. Fredrickson, M.D. 
Director .National Institutes of Health 
Bethesda, Md. 20014 
Dear Dr. Fredrickson: 
I received a copy of the Proposed Revised Guidelines for recombinant 
DNA research. I would like to convey my strong feeling that the proposed 
revisions are appropriate alterations in the existing Guidelines, and that 
they represent reasonable standards by which recombinant DNA research can 
be conducted safely and efficiently. 
I sincerely hope that the proposed revisions will be speedily approved. 
Sincerely , 
Nancy Kleckner 
Assistant Professor, Department of Biochemistry 
and Molecular Biology 
CA-79] 
