Department of Energy 
Washington, D.C. 20545 
SEP 1 2 W/tt 
Dr. Donald S. Fredrickson 
Director, National Institutes 
of Health 
Bethesda, Maryland 20014 
Dear Don: 
We have reviewed the Proposed Revised Guidelines for 
Recombinant DNA Research, and we give them our strong 
endorsement. Also, after they have become final we 
would place under voluntary registration all projects 
we support dealing with recombinant DNA. 
Sincerely, 
v? 
erman'- 
Deputy Assistant Secretary 
'for Environment 
[A-108] 
