UNIVERSITY OF CALIFORNIA. BERKELEY 
BERKELEY • DAVIS • IRVINE • LOS AKCELES • RIVERSIDE • SAN DIECO • SAN FRANCISCO 
SANTA BARBARA • SANTA CRUZ 
SCHOOL OF PUBLIC HEALTH 
NAVAL BIOSCIENCES LABORATORY 
NAVAL SUPPLY CENTER 
OAKLAND. CALIFORNIA 94625 
October 3, 1978 
Dr. DonaldS. Fredrickson, Director 
Department of Health, Education, 
and Welfare 
Public Health Service 
National Institutes of Health 
Bethesda, MD 20014 
Dear Dr. Fredrickson: 
I have just received the July 1978 "A Supplement to the NIH Guidelines 
for Recombinant DNA Research" which is entitled Laboratory Safety 
Monograph. 
This monograph is an excellent piece of work which should redound 
much to the credit of its authors. It has added clarity and logic to 
many of the physical and biological safety procedures described 
briefly in the guidelines. The monograph can stand alone as a 
substantial contribution in the field of microbiology laboratory 
safety. 
I am aware that the monograph was prepared by the Office Research 
Safety. As a person often critical of such public documents, I should 
like to say "well done". The monograph yields strong indication that 
the safety aspects of the recombinant DNA guidelines program is in 
good hands. 
Sincerely yours 
MAC :lf 
[A-413] 
