WISCONSIN ALUMNI RESEARCH FOUNDATION 
POST OFFICE BOX 73S5 • MADISON, WIS. B3707 • TELEPHONE (608) 263-2500 
September 9, 1976 263-2831 
Waclaw Szybalski, D. Sc. 
Professor of Oncology 
McArdle Laboratory 
University of Wisconsin 
Madison, Wisconsin 53706 
Dear Dr. Szybalski: 
Re: Recombinant DNA Advisory Committee 
We have the following comments in reference to Dr. Donald S. Fredrickson's 
letter on the above subject and our recent telephone conversation looking 
toward the September meeting of the Committee. 
Basically we believe that the terms and provisions of the extant Institutional 
Patent Agreement between the University of Wisconsin and the Department 
of Health, Education, and Welfare (DHEW) are sufficient to protect the public 
interest in this situation. In this regard the reporting requirements to DHEW 
and the march in rights which that Agency has (Article XII of the Institutional 
Patent Agreement) should be particularly emphasized. In addition, and over 
and above the protection afforded by such provisions, the Institutional Patent 
Agreement and presumably any deferred determination of ownership made by 
DHEW has the following provision. 
The Grantee shall not bar or prohibit publication of disclosures of 
inventions on which patent applications have been filed. 
The Grantor shall have the right to publish and make disclosure 
of any information relating to any subject invention whenever deemed 
to be in the public interest, provided that upon request reasonable 
opportunity shall be afforded the Grantee to file U. S. and foreign 
patent applications. 
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