The John A. Hartford Foun dation . I nc. 
Four Hundred Five Lex ngton Avenue 
New York, New '•'ork 10017 
November 22, 1976 
Donald S. Fredrickson, M.D., Director 
Department of Health, Education, and Welfare 
Public Health Service 
National Institutes of Health 
Bethesda, Maryland 20014 
Dear Doctor Fredrickson: 
This is in response to your November 17 letter to the 
Foundation's President, Harry B. George, inquiring as to this 
Foundation's conduct or support of recombinant DNA research. 
He has asked me to reply in my role as senior grant program 
administrator . 
The John A. Hartford Foundation has not supported research 
in this area, is not currently supporting any such projects, 
and future support is highly unlikely. Its major interests 
are in much more clinically-oriented biomedical studies. It 
does not conduct intramural research. 
In the event that such grant support might be extended 
at some future date, I am confident that the Foundation would 
insist that any such project be carried out in conformance 
with NIH guidelines. 
Further, among the terms on which this Foundation's 
grants for biomedical research are made which must be accepted 
by the grantee institution is this: "That in carrying out the 
purposes of the grant, the Grantee shall comply with all applic- 
able laws and regulations in force from time to time." 
C. G. Coburn 
Program Director 
CGC :his 
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