American 
Heart 
Association 
National Center Telephone 
ille Avenue 214 750-5448 
Dallas. Texas 75231 
March 30, 1977 
Donald S. Fredrickson, M.D. 
Di rector 
I National Institutes of Health 
f Building 1 , Room 124 
Bethesda, MD 20014 
Dear Don, 
I am writing in behalf of the American Heart Association Research 
Committee concerning actions it took at its recent meeting relating 
to human experimentation and recombinant DNA research. 
The Committee voted that in future the AHA Research Committee and 
all Research Study Conmittees will require applicants to affirm, 
where pertinent, that their research will conform to the National 
Institutes of Health Guidelines for Recombinant DNA Research and to 
those for Protection of Human Subjects. 
Another matter discussed and still unresolved is the inability of the 
NIH to provide any supplementation to AHA Established Investigators 
working in one of your Institutes. If you recall, you and I discussed 
very briefly at the AHA Annual Meeting last fall, problems relating to 
administration of potential El awards. 
Since 1973 the AHA has followed the practice of negotiating Established 
Investigator stipends with the sponsor institution so that the Associa- 
tion pays 75% and the El's institution pays 25% of the total annual 
salary according to the awardee's rank in relationship to his or her 
peers. The Association guarantees a minimum first-year salary of $15,000 
with annual increments of $1,000 and its maximum contribution to a nego- 
tiated (75%-25%) stipend is $26,000 for any of the five award years. The 
maximum allowable salary for a first year Ei is $37,000 and no more than 
two times the Association's maximum contribution ($26,000) for any sub- 
sequent year of the award. 
Virtually all of our Established Investigators receive institutional 
supplementation and it would seem timely that the National Institutes 
of Health explore the possibility of obtaining funds or a discretionary 
fund that would allow for some supplementation (however minor) to insure 
Chairman ot the Board 
President Elact 
[231] 
Vice Presidents 
T reasurer 
Richard Don, 
Harriet P Dustan. M D 
Philip P Arden, 
Owen Beard M D 
Ira L Lavm 
John G Martin 
John S Andrews 
Ptrndmt 
Immachata Past President 
John J DeFeo. Ph D 
Edward Mailman. M D 
Secretary 
John T Shepherd M D 
Eftot Rapaport M D 
Immadiata Pan 
Chairman o < lha Board 
Rom Raid 
Mrs Frank A Dresslar Jr 
Ham Jackson. M D 
Kenneth W Kihle M D 
Nanette K WengeT M D 
Stanford Wessler M D 
James G White. M D 
Mrs M Jeanne Ponoous, R N 
Executive Vice President 
William W Moore 
