The U.K. Guidelines require that researchers submit the details of 
their experiments to the U.K. GMAG for the assignment of a containment 
level. The GMAG, chaired by Sir Gordon Wolstenholme , is supported 
by the U.K. Medical Research Council and is responsible to the Secretary 
of State for Education and Science. It includes 19 representatives 
from industry, labor, the informed public, and the scientific community, 
and meets monthly to review proposals. 
Details of experiments must also be submitted to the Health and 
Safety Executive (HSE), for which the GMAG is the source of technical 
advice. HSE has authority under the Health and Safety at Work Act to 
monitor the workplace of all facilities. It maintains a force of inspec- 
tors with the authority to investigate industrial, governmental, and 
university laboratories. 
In August 1976 HSE circulated a draft consultative document contain- 
ing regulations directed specifically to the control of experiments 
involving genetic manipulation. The document includes a provision that 
would require prior approval of the GMAG and mandatory compliance with 
the physical-containment level recommended by the GMAG. This responsi- 
bility of the HSE will be activated in October 1978. 
As of September 1977, the U.K. GMAG had reviewed more than 100 
applications. None in progress has yet required maximum containment. 
UNION OF SOVIET SOCIALIST REPUBLICS 
Little information is available, but a Committee on Recombinant DNA 
Molecules, chaired by Professor Bayev, has drafted a set of guidelines. 
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