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to, and safety techniques to be followed by, per- 
sonnel to be involved in such activities, 
“(II) monitoring systems to protect against 
accidental exposure and other hazards to the health 
of such personnel while engaged in such activities, 
“ (III) the type and form of information to be 
given such personnel concerning the nature of the 
health risks presented by such activities and the 
frequency and manner of giving them such informa- 
tion, and 
“(IV) the type and frequency of medical 
examinations to be given such personnel while en- 
gaged in such activities ; 
“ (iii) prescribe requirements respecting reports to 
be made and records to be maintained by the holders 
of licenses issued under this section ; 
“(iv) include such special requirements as the 
Secretaiy determines necessary for the conduct of recom- 
binant DNA activities involving more than ten liters 
of cell cultures containing recombinant DNA and for the 
conduct of any commercial recombinant DNA activity 
which the Secretary determines may present a signifi- 
cant risk to the public health and safety or the environ- 
ment; and 
[ 588 ] 
