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“(II) I)NA segments which are derived 
from plasmids of prokaryotic cells, 
“(III) DNA segments which are derived 
from the DNA of viruses which can only infect 
prokaryotic cells, or 
“ (IV) any combi’ nation of such DNA seg- 
ments, 
and which DNA molecules can only enter and 
replicate in cells in which each DNA segment from 
which such DNA molecules were formed can also 
enter and replicate hy a process which the Secretary 
determines is known to occur naturally; or 
“ (ii) which consist entirely of DNA segments 
from a single nonchromosomal DNA source. 
“(3) The term ‘local biohazards committee’ means 
a local biohazards committee established in accordance 
with section 476, and the term ‘Advisory Committee’ 
means the Recombinant DNA Advisory Committee 
established under section 481. 
“ (4) The possession in a State of recombinant 
DNA by any individual or public or private entity and 
any activity (including research and transportation) 
undertaken in a State by any individual or public or 
private entity for the production of recombinant DNA 
are collectively referred to as ‘recombinant DNA a. iiv- 
[ 621 ] 
