18 
1 ducted under the license will be conducted in accordance 
2 with applicable physical and biological containment re- 
3 quirements prescribed under subsection (a) (3) (A) (i) ; 
4 “(3) assurances satisfactory to the issuer of the 
5 license that in that conduct of each such activity there 
6 will be compliance with applicable personnel safety 
7 requirements prescribed under subsection (a) (3) (A) 
8 (ii) ; 
9 “ (4) assurances satisfactory to the issuer of the 
10 license that the holder of the license shall make such re- 
11 ports, and shall maintain such records, respecting each 
12 such activity (including reports and records of any sig- 
13 nificant or recurring illness, serious injury, or death of 
14 any personnel engaged in such activity and of the 
15 health care provided such personnel while engaged in 
16 such activity) as are required under subsection (a) (3) 
17 (A) (iii) ; 
18 “(5) a comprehensive statement of the results of 
19 any evaluation made by or known to the applicant of 
20 the risks to health or the environment which may be 
21 presented by any recombinant DNA activity to be 
22 conducted under the license; and 
23 “(6) such additional information as the Secretary 
24 may prescribe. 
25 Applications for the amendment of a license shall contain 
[ 636 ] 
