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DNA molecules must propagate within the host cell by proc- 
esses which are known to occur naturally there. 
“(C) The Commission shall not exempt DNA molecules 
under subparagraph (B) from the definition in subpara- 
graph (A) unless the Commission determines that such mole- 
cules do not present an unreasonable risk to the health of the 
persons exposed to such molecules, to the environment, or 
to the health of the public. 
“(3) ‘ Recombinant DNA activities' means any research, 
study, investigation, experiment, or activity in connection 
with recombinant DNA. 
“(4) ‘ Hazardous product of recombinant DNA activi- 
ties' means a biological or chemical product of recombinant 
DNA activities which is handled, treated, or contained in 
such a manner as to pose a significant risk to health or to the 
environment, as determined by the Commission. 
“(5) ‘ Commerce ' means any activity which affects (1) 
commerce between any State or territory and any place out- 
side thereof, and (2) commerce within the District of Co- 
lumbia or within any other territory not organized with a 
legislative body, 
“(6) ‘ Commission ' means the National Recombinant 
DNA Regulation Commission, established under section 
1801, 
“(7) ‘ Construction of a facility ' means a facility which 
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