2 
(2) Require that all recombinant DNA activities must be con- 
ducted in facilities licensed by the Commission according to regu- 
lations promulgated by the Commission ; 
(3) Authorize the Commission to promulgate safety regulations 
with respect to recombinant DNA activities, to prescribe the re- 
quirements for licensure of facilities that are used for the conduct 
of recombinant DNA activities, and to prescribe requirements for 
the establishment and functions of Institutional Biohazards Re- 
view Committees ; 
(4) Authorize the Commission to prepare and transmit to the 
Congress a comprehensive study that identifies the basic ethical 
and scientific principles which should underlie the conduct, ap- 
plications and use of recombinant DNA activities; 
(5) Prescribe the conditions for which the Commission may 
revoke, suspend or limit the license of a facility ; 
( 6 ) Authorize the Commission to conduct initial and annual 
inspections of facilities where recombinant DNA activities are 
being conducted, and prescribes on order and conditions for such 
inspections ; 
(7) Provide for administrative restraint, seizure or destruction 
of hazardous products of recombinant DNA activities; 
( 8 ) Supersede any and all laws of state and their political sub- 
divisions that establish or continue in effect any requirement with 
respect to recombinant DNA activities; but authorizes the Com- 
mission to provide for exemptions, to federal preemption if the 
application from state and local political divisions meet the neces- 
sary conditions ; 
( 10 ) Prescribe the procedures for the protection and disclosure 
of data ; 
(11) Require that a recombinant DNA project be approved by 
the local Institutional Biohazards Committee ; 
(12) Direct that no Federal funds be expended for more than 
50 percent of the actual cost of construction of a facility'' for the 
purpose of meeting the highest level of physical containment 
requirements; and 
(13) Authorize that such sums as necessary be appropriated 
for fiscal 3 'ears 1978, 1979, 1980, 1981, and 1982. 
II. Background and Definition of the Issue 
Recombinant DNA research enables scientists to isolate bits of 
genetic material from an organism and recombine them with similar 
material from related or unrelated plants or animal species. The 
acronym DNA comes from the chemical name deoxyribonucleic acid, 
the material that makes up all genes. 
Research involving recombinant DNA has been a controversial issue 
within the scientific community for some time. As people outside of 
research circles have become more and more aware of the work, the 
public has become involved. In a number of local communities around 
the country, public actions have been taken. These actions have served 
to highlight the controversy over genetic recombination and have also 
provided a unique example of citizen participation in decison making 
with regard to the conditions under which DNA activities should 
be carried out. 
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