39 
“(e) The Commission snail not issue an initial license unless it Tias 
determined that , 'prior to engaging in recombinant DNA activities 
at the facility — 
“(i) all the requirements of this title will be met; and 
“(2) the recombinant DNA activities to be conducted in the 
facility to be licensed will be conducted in a manner as to pro- 
tect the health of the persons exposed to recombinant DNA , pro- 
tect the environment , and protect the health of the population 
of the surrov/nding community. 
“ (/) The Commission shall not issue a renewal of a license unless 
it has determined that — 
“(1) all the requirements of this title have been met ; and 
“(2) the recombinant DNA activities which have been con- 
ducted in the facility , which teas previously licensed under this 
title , were conducted in a manner as to protect the health of 
the persons exposed to recombinant DNA , protect the environ- 
ment , and protect the health of the population of the surround- 
ing community. 
“ (g) Effective one hundred and fifty days after the date of enact- 
ment of this title , no person may engage in recombinant DNA activi- 
ties in the States , or in any area subject to the jurisdiction of the 
United States unless such activities comply with the regulations 
promulgated under section 1801(a) (1) or until licensed under section 
1803. 
“ LICENSING REQUIREMENTS 
“Sec. 180 Jj. (a) For purposes of protecting the health and safety of 
individuals who work with recombinant DNA , the health and safety 
of the public at large , and the integrity of the environment , the Com- 
mission shall — 
“(1) no later than one hundred and twenty days after the date 
of enactment of this title , promulgate , as final , regulations which 
prescribe physical and biological containment requirements for 
recombinant DNA activities which during the, one hundred and 
eighty day period beginning on the date of the promulgation of 
regulations u/nder this paragraph shall be no less stringent than 
the physical and biological containment requirements prescribed 
by the recombinant DNA Research Guidelines of the National In- 
stitutes of Health which are in effect on the date of enactment of 
this title; 
“(2) no later than ninety days after the date of promulgation 
of final regulations under paragraph (1 ) , promulgate regulations 
to implement the license and other requirements prescribed by this 
title. Including the requirements promulgated under paragraph 
(1) of this subsection , amended , if necessary , the regulations 
shall — 
“(A) prescribe requirements respecting laboratory safety 
techniques and monitoring to be followed by persons author- 
ized by a license to engage in recombinant DNA activities in 
connection with the licensed facility , including — 
“ (i) the laboratory safety training to be given to , and 
the safety techniques to be followed by , personnel in- 
volved in such activities , 
[ 779 ] 
