41 
“(Hi) providing for public notice to the local communities 
by such committee of each recombinant DNA project ap- 
proved by such committees. 
“(D) prescribe requirements respecting the possession and han- 
dling of recombinant DN A and the biological or chemical products 
of recombinant DN A activities outside of a. licensed facility or 
in commerce ; 
“ (E) prescribe requirements respecting records and reports, 
related to the safety of recombinant DN A activities , to be main- 
tained and submitted by — 
“ (i) persons who own or operate the facility licensed under 
section 1803; and 
u (ii) persons who are authorized by' a license to engage in 
recombinant DNA activities in connection with the licensed 
facility ; 
“(F) prescribe requirements respecting the responsibilities of 
owners or operators of a facility licensed under section 1803 to 
•monitor compliance of the facility and, persons authorized by the 
license to engage in recombinant DNA activities in connection 
with the licensed facility with the requirements of this title; and 
“(G) include such other provisions related to the safety of re- 
combinant- DN A activities as the Commission determines to be 
necessary for carrying out the provisions of this title. 
“(b)(1) The Commission shall periodically review regulations 
promulgated under subsection (a) and promulgate' such amendments 
to such regulations as it determines to be necessary. 
“ (2) (A ) Upon promulgation of a proposed regulation which would 
be more stringent than an existing f had regulation promulgated under 
Subsection (a), the Commission shall provide notice, in accordance 
with subparagraph (C) . to each state and political subdivision which 
has been granted an exempt requirement. 
“(B) During the review and comment period for such proposed 
regulation, the Commission shall make a . determination as to the effect 
of such regulation , when final, on each exempt requirement. If the 
Commission determines that such regulation would , when final, super- 
cede any exempt requirement, the Commission shall provide notice , in 
accordance with subparagraph (C), to each state and political sub- 
division which has an exempt requirement. 
“(C) The Commission shall provide notice, as required under sub- 
paragraphs (A) and (B) by sending, in writing and through certi- 
fied maid — 
“ (i) a copy of the proposed or final regulation; 
“(ii) a statement that such proposed or final regulation may 
supersede the exempt requirement of the state or political 
subdivision; 
“ (Hi) a letter, signed by the Chairman of the Commission, in- 
forming the state or political subdivision that the Com/mission 
has made the determination, required by subparagraph (B), and 
the effect of such determination on the exempt requirem.ent of such 
State or political subdivision; 
“(iv) a time schedule of when the proposed or final regulation 
would become effective. 
[ 781 ] 
