Recombinant DNA Advisory Committee - 7/31/90 
* * * TABLE OP CONTENTS * * * 
CALL TO ORDER: 
Dr. McGarrity 1 
MINUTES OF THE MARCH 30, 1990 MEETING: 
Dr. Riley 3 
PRESENTATION AND DISCUSSION OF PROPOSED ADDITION TO 
APPENDIX D OF THE "NIH GUIDELINES" REGARDING HUMAN 
GENE THERAPY PROTOCOL ENTITLED "TREATMENT OF SEVERE 
COMBINED IMMUNODEFICIENCY DISEASE (SCID) DUE TO 
ADENOSINE DEAMINASE DEFICIENCY WITH AUTOLOGOUS 
LYMPHOCYTES TRANSDUCED WITH A HUMAN ADA GENE": 
Dr. Gellert 3 
PROPOSED ADDITION TO APPENDIX D OF THE "NIH 
GUIDELINES" REGARDING HUMAN GENE THERAPY PROTOCOL 
ENTITLED "GENE THERAPY OF PATIENTS WITH ADVANCED 
CANCER USING TUMOR INFILTRATING LYMPHOCYTES 
TRANSDUCED WITH THE GENE CODING FOR TUMOR 
NECROSIS FACTOR": 
Dr. Mclvor 8 
PRESENTATION AND DISCUSSION OF PROPOSED ADDITION 
TO THE "POINTS TO CONSIDER" DOCUMENT TO EXPEDITE 
MINOR MODIFICATION ON APPROVED PROTOCOLS: 
Dr. R. Murray 16 
PROPOSED ADDITION TO APPENDIX D OF THE "NIH 
GUIDELINES" REGARDING HUMAN GENE TRANSFER 
CLINICAL PROTOCOL ENTITLED "USE OF MARKER 
GENES TO INVESTIGATE THE BIOLOGY OF MARROW 
RECONSTITUTION AND RELAPSE OF MALIGNANT 
DISEASE FOLLOWING AUTOLOGOUS BONE MARROW 
TRANSPLANTATION" : 
Dr. Mulligan 2 0 
DISCUSSION ON REVISION OF APPENDIX K 
OF THE "NIH GUIDELINES": 
Dr. Riley 2 3 
REGIONAL PUBLIC HEARINGS: 
Dr. Wivel 2 5 
FUTURE MEETING DATES OF THE RAC: 
Dr. McGarrity 2 7 
ADJOURNMENT: 
Dr. McGarrity 2 7 
Recombinant DNA Research, Volume 14 
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