Title: Treatment of Severe Combined Immunodeficiency Disease (SCID) due to Adenosine 
Deaminase (ADA) Deficiency with Autologous Lymphocytes Transduced with a Human 
ADA Gene 
Principal Investigator: 
R. Michael Blaese, M.D., Chief, Cellular Immunology Section, 
Metabolism Branch; NCI phone (301) 496-5396 
Research Nurse: 
Lois Top, R.N. phone (301) 496-4703 
Associate investigators: 
W. French Anderson, M.D., Chief, Molecular Hematology Branch, NHLBI 
Kenneth W. Culver, M.D., Medical Staff Fellow, Cellular Immunology Section, 
Metabolism Branch, NCI 
Steven A. Rosenberg, M.D., Chief, Surgery Branch, NCI 
Major Collaborators: 
Melvin Berger, M.D., Associate Professor of Pediatrics and Pathology, Case Western 
Reserve School of Medicine 
Claudio Bordignon, M.D., Department of Laboratory Medicine, H. S. R., Milan, Italy 
Steven D. Douglas, M.D., Director of Allergy and Immunology, Children’s Hospital, 
Philadelphia 
Thomas Fleisher, M.D., Chief, Immunology Service, Clinical Pathology Department, 
Clinical Center, NIH 
A. Dusty Miller, Ph.D., Associate Member, Fred Hutchinson Cancer Research Center, 
Seattle, WA 
E. Richard Stiehm, M.D., Professor of Pediatrics, U.C.L.A, School of Medicine 
Other Contributors 
Paul Aebersold, Yawen Chiang, Martin Eglitis, Scott Freeman, Eli Gilboa, Don Kohn, 
Dan Kuebbing, Jeanne McLachlin, Bob Moen, Richard Morgan, Richard O’Reilly, Bill 
Osborne 
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Recombinant DNA Research, Volume 14 
