Page 6 - Revision of the Guidelines Subcommittee - 10/15/90 
'Appendix K -* Comparison of GILSP and BL*LS Criteria. 
CRITERION^ 
1. Formulates and implement institutional 
codes of practice for safety of personnel 
and adequate control of hygiene and safety 
measures. 
2. Provide adequate written instructions and 
training of personnel to keep the work- 
place clean and tidy and to keep exposure 
to biological, chemical or physical 
agents at a level that does not adversely 
affect the health and safety of employees. 
3. Provide changing and handwashing 
facilities as well as protective 
clothing, appropriate to the risk, to 
be worn during work. 
4. Prohibit eating, drinking, smoking, mouth 
pipetting, and applying cosmetics in the 
workplace. 
5. Internal accident reporting. 
6. Medical surveillance. 
7. Viable organisms should be handled in a 
system that physically separates the 
process from the external environment 
(closed system or other primary 
containment equipment). 
8. Organisms inactivated prior to removal 
from a system. 
9. Treatment of exhaust gases from a system. 
10. Performance of seals. 
11. Control of aerosols during: 
a. Sampling from a system. 
b. Addition of materials to a system; 
transfer of cultivated cells. 
c. Removal of material, products and 
effluents from a system. 
NIH-RAC 
GILSP'^ 
BL1-LS 
BL2-LS 
BL3-LS 
Requi red 
Requi red 
Requi red 
Requi red 
Requi red 
Required 
Requi red 
Required 
Requi red 
Required 
Requi red 
Required 
Requi red 
Required 
Requi red 
Requi red 
Requi red 
Requi red 
Requi red 
Requi red 
Not required 
Not required 
Requi red 
Required 
Not required 
Requi red 
Requi red 
Required 
Not required 
Requi red 
Requi red 
Requi red 
Not required 
Minimize 
release 
Prevent 
release 
Prevent 
release 
Not required 
Minimize 
release 
Prevent 
release 
Prevent 
release 
Minimize 
release 
through 
procedural 
controls 
Minimize 
release 
through 
engineering 
controls 
Prevent 
release 
Prevent 
release 
Minimize 
release 
through 
procedural 
controls 
Minimize 
release 
through 
engineering 
controls 
Prevent 
release 
Prevent 
release 
Minimize 
release 
through 
procedural 
controls 
Minimize 
release 
through 
engineering 
controls 
Prevent 
release 
Prevent 
release 
Recombinant DNA Research, Volume 14 
[321] 
