37848 . Federal Regi. / Vol. 65, No. 178 / Thursday, Septembe.. , 1990 / Notices 
"Appendix Comparison of &ILSP and BL-LS Criteria. 
WIH-RAC 
CRITERIOM^ 
GILSP^ 
BL1-LS 
BL2-LS 
BL3-LS 
1. Formulates and implement institutional 
Required 
Required 
Required 
. Requi red 
codes of. practice for, safety of personnel 
and adequate ’control of hygiene and safety 
'measures'j ■ 
2. Provide adequate written instructions and 
training of persomWl to keep the work- 
, place clean and tidy and to keep exposure 
to biological*, chemical or. physical 
Required 
Rel^ired 
Required 
Required 
agents at .a ^vel that does, not adversely 
affect ;the health ;qind.s;afety of rcmployees. 
• . f 1 . 
3. Provide changing and handwashing 
Required 
Required 
Requi red 
Requi red 
’facilities as well as protective 
clothing, appropriate to the risk, to 
be worn during work. 
4. Prohibit eatir^, drinking, smoking, mouth 
Required 
Requi red 
Required 
Requi red 
pipetting, and applying cosmetics in the 
workplace. 
5. Internal accident reporting. 
Required 
Required 
Requi red 
Required 
6. Medical surveillance. 
Not required 
Not required 
Required 
Required 
7. Viable organisms should be handled in a 
Not required 
Required 
Required 
Required 
system that physically separates the 
process from the external environment 
Iclosed system or other- primary 
containment equipment). 
' ‘ ■ 
8. Organisms inactivated prior to removal 
from a system. . 
Not required 
Requi red 
Required 
Required 
9. Treatment of exhaust gases’ from a system. 
Not required 
Minimize 
release 
Prevent 
release 
Prevent 
release 
10. Performance of seals. 
Not required 
Minimi ze 
release 
Prevent 
release 
Prevent 
release 
11. Control of aerosols during: 
a. Sampling from a system. 
Minimize 
release 
through 
procedural 
controls 
Minimize 
release 
through 
engineering 
controls 
Prevent 
release 
Prevent 
release 
. :b. Addition of materials to a system;: 
Minimize 
Minimize 
Prevent 
Prevent 
transfer of cultivated cells. , 
release 
throuigh 
procedural 
controls : 
release <• 
through 
engineering 
controls 
release 
release 
c. Removal ’'of material;, products and 
Minimize 
Minimize 
Prevent 
Prevent 
affluents frjbm a system. 
release 
through 
procedural 
controls 
release 
through 
engineering 
controls 
release 
release 
Recombinant DNA Research, Volume 14 
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